Do trauma-focussed psychological interventions have an effect on psychotic symptoms? A systematic review and meta-analysis.
Identifieur interne : 000F53 ( Main/Exploration ); précédent : 000F52; suivant : 000F54Do trauma-focussed psychological interventions have an effect on psychotic symptoms? A systematic review and meta-analysis.
Auteurs : Rachel M. Brand [Australie] ; Carla Mcenery [Australie] ; Susan Rossell [Australie] ; Sarah Bendall [Australie] ; Neil Thomas [Australie]Source :
- Schizophrenia research [ 1573-2509 ] ; 2018.
Descripteurs français
- KwdFr :
- MESH :
- méthodes : Psychothérapie.
- rééducation et réadaptation : Troubles de stress post-traumatique, Troubles psychotiques.
- étiologie : Troubles psychotiques.
- complications : Humains, Schizophrénie, Troubles de stress post-traumatique.
English descriptors
- KwdEn :
- MESH :
- complications : Schizophrenia, Stress Disorders, Post-Traumatic.
- etiology : Psychotic Disorders.
- methods : Psychotherapy.
- rehabilitation : Psychotic Disorders, Stress Disorders, Post-Traumatic.
- Humans.
Abstract
There is growing recognition of the relationship between trauma, posttraumatic stress disorder (PTSD) and psychosis. There may be overlaps in causal mechanisms involved in the development of PTSD and psychosis following traumatic or adverse events. Trauma-focussed treatments found to be effective in treating PTSD may therefore represent a new direction in the psychological treatment of psychosis. This systematic review examined the literature on trauma-focussed treatments conducted with people with schizophrenia spectrum or psychotic disorders to determine effects on psychotic symptoms. Secondary outcomes were symptoms of PTSD, depression and anxiety. Twenty-five studies were included in the review, with 12 being included in the meta-analysis. Trauma-focussed treatments had a small, significant effect (g=0.31, CI [0.55, 0.06]) on positive symptoms immediately post-treatment, but the significance and magnitude of this effect was not maintained at follow-up (g=0.18, CI [0.42, -0.06]). Trauma-focussed treatments also had a small effect on delusions at both post-treatment (g=0.37, CI [0.87, -0.12]) and follow-up (g=0.38, CI [0.67, 0.10]), but this only reached significance at follow-up. Effects on hallucinations and negative symptoms were small and non-significant. Effects on PTSD symptoms were also small (post-treatment g=0.21, CI [0.70, -0.27], follow up g=0.31, CI [0.62, 0.00]) and only met significance at follow-up. No significant effects were found on symptoms of depression and anxiety. Results show promising effects of trauma-focussed treatments for the positive symptoms of psychosis, however further studies developing and evaluating trauma-focussed treatments for trauma-related psychotic symptoms are needed.
DOI: 10.1016/j.schres.2017.08.037
PubMed: 28844432
Affiliations:
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A systematic review and meta-analysis.</title><author><name sortKey="Brand, Rachel M" sort="Brand, Rachel M" uniqKey="Brand R" first="Rachel M" last="Brand">Rachel M. Brand</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Mental Health, Swinburne University, PO Box 218, Hawthorn, VIC 3122, Australia; The Voices Clinic, Monash Alfred Psychiatry Research Centre, Alfred Hospital, Monash University Central Clinical School, Melbourne, VIC 3004, Australia. Electronic address: rbrand@swin.edu.au.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Mental Health, Swinburne University, PO Box 218, Hawthorn, VIC 3122, Australia; The Voices Clinic, Monash Alfred Psychiatry Research Centre, Alfred Hospital, Monash University Central Clinical School, Melbourne, VIC 3004</wicri:regionArea><wicri:noRegion>VIC 3004</wicri:noRegion></affiliation></author><author><name sortKey="Mcenery, Carla" sort="Mcenery, Carla" uniqKey="Mcenery C" first="Carla" last="Mcenery">Carla Mcenery</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Mental Health, Swinburne University, PO Box 218, Hawthorn, VIC 3122, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Mental Health, Swinburne University, PO Box 218, Hawthorn, VIC 3122</wicri:regionArea><wicri:noRegion>VIC 3122</wicri:noRegion></affiliation></author><author><name sortKey="Rossell, Susan" sort="Rossell, Susan" uniqKey="Rossell S" first="Susan" last="Rossell">Susan Rossell</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Mental Health, Swinburne University, PO Box 218, Hawthorn, VIC 3122, Australia; The Voices Clinic, Monash Alfred Psychiatry Research Centre, Alfred Hospital, Monash University Central Clinical School, Melbourne, VIC 3004, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Mental Health, Swinburne University, PO Box 218, Hawthorn, VIC 3122, Australia; The Voices Clinic, Monash Alfred Psychiatry Research Centre, Alfred Hospital, Monash University Central Clinical School, Melbourne, VIC 3004</wicri:regionArea><wicri:noRegion>VIC 3004</wicri:noRegion></affiliation></author><author><name sortKey="Bendall, Sarah" sort="Bendall, Sarah" uniqKey="Bendall S" first="Sarah" last="Bendall">Sarah Bendall</name><affiliation wicri:level="4"><nlm:affiliation>Orygen: The National Centre of Excellence in Youth Mental Health, 35 Poplar Road, Parkville, VIC 3052, Australia; The Centre for Youth Mental Health, The University of Melbourne, VIC 3010, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Orygen: The National Centre of Excellence in Youth Mental Health, 35 Poplar Road, Parkville, VIC 3052, Australia; The Centre for Youth Mental Health, The University of Melbourne, VIC 3010</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Thomas, Neil" sort="Thomas, Neil" uniqKey="Thomas N" first="Neil" last="Thomas">Neil Thomas</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Mental Health, Swinburne University, PO Box 218, Hawthorn, VIC 3122, Australia; The Voices Clinic, Monash Alfred Psychiatry Research Centre, Alfred Hospital, Monash University Central Clinical School, Melbourne, VIC 3004, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Mental Health, Swinburne University, PO Box 218, Hawthorn, VIC 3122, Australia; The Voices Clinic, Monash Alfred Psychiatry Research Centre, Alfred Hospital, Monash University Central Clinical School, Melbourne, VIC 3004</wicri:regionArea><wicri:noRegion>VIC 3004</wicri:noRegion></affiliation></author></analytic><series><title level="j">Schizophrenia research</title><idno type="eISSN">1573-2509</idno><imprint><date when="2018" type="published">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Humans (MeSH)</term><term>Psychotherapy (methods)</term><term>Psychotic Disorders (etiology)</term><term>Psychotic Disorders (rehabilitation)</term><term>Schizophrenia (complications)</term><term>Stress Disorders, Post-Traumatic (complications)</term><term>Stress Disorders, Post-Traumatic (rehabilitation)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Humains (MeSH)</term><term>Psychothérapie (méthodes)</term><term>Schizophrénie (complications)</term><term>Troubles de stress post-traumatique (complications)</term><term>Troubles de stress post-traumatique (rééducation et réadaptation)</term><term>Troubles psychotiques (rééducation et réadaptation)</term><term>Troubles psychotiques (étiologie)</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Schizophrenia</term><term>Stress Disorders, Post-Traumatic</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Psychotic Disorders</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Psychotherapy</term></keywords><keywords scheme="MESH" qualifier="méthodes" xml:lang="fr"><term>Psychothérapie</term></keywords><keywords scheme="MESH" qualifier="rehabilitation" xml:lang="en"><term>Psychotic Disorders</term><term>Stress Disorders, Post-Traumatic</term></keywords><keywords scheme="MESH" qualifier="rééducation et réadaptation" xml:lang="fr"><term>Troubles de stress post-traumatique</term><term>Troubles psychotiques</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Troubles psychotiques</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="fr"><term>Humains</term><term>Schizophrénie</term><term>Troubles de stress post-traumatique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">There is growing recognition of the relationship between trauma, posttraumatic stress disorder (PTSD) and psychosis. There may be overlaps in causal mechanisms involved in the development of PTSD and psychosis following traumatic or adverse events. Trauma-focussed treatments found to be effective in treating PTSD may therefore represent a new direction in the psychological treatment of psychosis. This systematic review examined the literature on trauma-focussed treatments conducted with people with schizophrenia spectrum or psychotic disorders to determine effects on psychotic symptoms. Secondary outcomes were symptoms of PTSD, depression and anxiety. Twenty-five studies were included in the review, with 12 being included in the meta-analysis. Trauma-focussed treatments had a small, significant effect (g=0.31, CI [0.55, 0.06]) on positive symptoms immediately post-treatment, but the significance and magnitude of this effect was not maintained at follow-up (g=0.18, CI [0.42, -0.06]). Trauma-focussed treatments also had a small effect on delusions at both post-treatment (g=0.37, CI [0.87, -0.12]) and follow-up (g=0.38, CI [0.67, 0.10]), but this only reached significance at follow-up. Effects on hallucinations and negative symptoms were small and non-significant. Effects on PTSD symptoms were also small (post-treatment g=0.21, CI [0.70, -0.27], follow up g=0.31, CI [0.62, 0.00]) and only met significance at follow-up. No significant effects were found on symptoms of depression and anxiety. Results show promising effects of trauma-focussed treatments for the positive symptoms of psychosis, however further studies developing and evaluating trauma-focussed treatments for trauma-related psychotic symptoms are needed.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28844432</PMID><DateCompleted><Year>2018</Year><Month>11</Month><Day>19</Day></DateCompleted><DateRevised><Year>2018</Year><Month>12</Month><Day>02</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1573-2509</ISSN><JournalIssue CitedMedium="Internet"><Volume>195</Volume><PubDate><Year>2018</Year><Month>05</Month></PubDate></JournalIssue><Title>Schizophrenia research</Title><ISOAbbreviation>Schizophr Res</ISOAbbreviation></Journal><ArticleTitle>Do trauma-focussed psychological interventions have an effect on psychotic symptoms? A systematic review and meta-analysis.</ArticleTitle><Pagination><MedlinePgn>13-22</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0920-9964(17)30513-3</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.schres.2017.08.037</ELocationID><Abstract><AbstractText>There is growing recognition of the relationship between trauma, posttraumatic stress disorder (PTSD) and psychosis. There may be overlaps in causal mechanisms involved in the development of PTSD and psychosis following traumatic or adverse events. Trauma-focussed treatments found to be effective in treating PTSD may therefore represent a new direction in the psychological treatment of psychosis. This systematic review examined the literature on trauma-focussed treatments conducted with people with schizophrenia spectrum or psychotic disorders to determine effects on psychotic symptoms. Secondary outcomes were symptoms of PTSD, depression and anxiety. Twenty-five studies were included in the review, with 12 being included in the meta-analysis. Trauma-focussed treatments had a small, significant effect (g=0.31, CI [0.55, 0.06]) on positive symptoms immediately post-treatment, but the significance and magnitude of this effect was not maintained at follow-up (g=0.18, CI [0.42, -0.06]). Trauma-focussed treatments also had a small effect on delusions at both post-treatment (g=0.37, CI [0.87, -0.12]) and follow-up (g=0.38, CI [0.67, 0.10]), but this only reached significance at follow-up. Effects on hallucinations and negative symptoms were small and non-significant. Effects on PTSD symptoms were also small (post-treatment g=0.21, CI [0.70, -0.27], follow up g=0.31, CI [0.62, 0.00]) and only met significance at follow-up. No significant effects were found on symptoms of depression and anxiety. Results show promising effects of trauma-focussed treatments for the positive symptoms of psychosis, however further studies developing and evaluating trauma-focussed treatments for trauma-related psychotic symptoms are needed.</AbstractText><CopyrightInformation>Copyright © 2017 Elsevier B.V. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Brand</LastName><ForeName>Rachel M</ForeName><Initials>RM</Initials><AffiliationInfo><Affiliation>Centre for Mental Health, Swinburne University, PO Box 218, Hawthorn, VIC 3122, Australia; The Voices Clinic, Monash Alfred Psychiatry Research Centre, Alfred Hospital, Monash University Central Clinical School, Melbourne, VIC 3004, Australia. Electronic address: rbrand@swin.edu.au.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>McEnery</LastName><ForeName>Carla</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Centre for Mental Health, Swinburne University, PO Box 218, Hawthorn, VIC 3122, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rossell</LastName><ForeName>Susan</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Centre for Mental Health, Swinburne University, PO Box 218, Hawthorn, VIC 3122, Australia; The Voices Clinic, Monash Alfred Psychiatry Research Centre, Alfred Hospital, Monash University Central Clinical School, Melbourne, VIC 3004, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bendall</LastName><ForeName>Sarah</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Orygen: The National Centre of Excellence in Youth Mental Health, 35 Poplar Road, Parkville, VIC 3052, Australia; The Centre for Youth Mental Health, The University of Melbourne, VIC 3010, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Thomas</LastName><ForeName>Neil</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Centre for Mental Health, Swinburne University, PO Box 218, Hawthorn, VIC 3122, Australia; The Voices Clinic, Monash Alfred Psychiatry Research Centre, Alfred Hospital, Monash University Central Clinical School, Melbourne, VIC 3004, Australia.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D017418">Meta-Analysis</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType><PublicationType UI="D016454">Review</PublicationType><PublicationType UI="D000078182">Systematic Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>08</Month><Day>24</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>Schizophr Res</MedlineTA><NlmUniqueID>8804207</NlmUniqueID><ISSNLinking>0920-9964</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011613" MajorTopicYN="N">Psychotherapy</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011618" MajorTopicYN="N">Psychotic Disorders</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName><QualifierName UI="Q000534" MajorTopicYN="Y">rehabilitation</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012559" MajorTopicYN="N">Schizophrenia</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013313" MajorTopicYN="N">Stress Disorders, Post-Traumatic</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000534" MajorTopicYN="Y">rehabilitation</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">Meta-analysis</Keyword><Keyword MajorTopicYN="Y">Posttraumatic stress disorder</Keyword><Keyword MajorTopicYN="Y">Psychosis</Keyword><Keyword MajorTopicYN="Y">Schizophrenia</Keyword><Keyword MajorTopicYN="Y">Trauma</Keyword><Keyword MajorTopicYN="Y">Treatment</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>11</Month><Day>16</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2017</Year><Month>08</Month><Day>15</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>08</Month><Day>18</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>8</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2018</Year><Month>11</Month><Day>20</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>8</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28844432</ArticleId><ArticleId IdType="pii">S0920-9964(17)30513-3</ArticleId><ArticleId IdType="doi">10.1016/j.schres.2017.08.037</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Australie</li></country><region><li>Victoria (État)</li></region><settlement><li>Melbourne</li></settlement><orgName><li>Université de Melbourne</li></orgName></list><tree><country name="Australie"><noRegion><name sortKey="Brand, Rachel M" sort="Brand, Rachel M" uniqKey="Brand R" first="Rachel M" last="Brand">Rachel M. Brand</name></noRegion><name sortKey="Bendall, Sarah" sort="Bendall, Sarah" uniqKey="Bendall S" first="Sarah" last="Bendall">Sarah Bendall</name><name sortKey="Mcenery, Carla" sort="Mcenery, Carla" uniqKey="Mcenery C" first="Carla" last="Mcenery">Carla Mcenery</name><name sortKey="Rossell, Susan" sort="Rossell, Susan" uniqKey="Rossell S" first="Susan" last="Rossell">Susan Rossell</name><name sortKey="Thomas, Neil" sort="Thomas, Neil" uniqKey="Thomas N" first="Neil" last="Thomas">Neil Thomas</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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